Tuesday, April 4, 2017

Science News Today


Mayo Clinic Researchers Demonstrate Value of Second Opinions
Many patients come to Mayo Clinic for a second opinion or diagnosis confirmation before treatment for a complex condition. In a new study, Mayo Clinic reports that as many as 88 percent of those patients go home with a new or refined diagnosis — ch...
– Mayo Clinic
Journal of Evaluation in Clinical Practice
Embargo expired on 04-Apr-2017 at 04:00 ET


Study Reverses Thinking on Genetic Links to Stress, Depression
For years, scientists have been trying to determine what effect a gene linked to the brain chemical serotonin may have on depression in people exposed to stress. But now, analyzing information from more than 40,000 people who have been studied over m...
– Washington University in St. Louis
Molecular Psychiatry, April 4, 2017
Embargo expired on 04-Apr-2017 at 03:00 ET


Disrupted Brain Pathway, Altered Stress Hormones Key to TBI Impact Differences in Men, Women
The brains of men and women are wired differently, and when it comes to traumatic brain injuries (TBI), women are more likely to develop subsequent neuropsychiatric disorders, like anxiety, depression and post-traumatic stress disorder. Until now, it...
– Uniformed Services University of the Health Sciences (USU)
Embargo expired on 03-Apr-2017 at 13:00 ET


Deploying an Ancient Defense to Kill Cancer
What if your body’s ancient defenses against invading bacteria could be hijacked to help kill cancer? In a small sarcoma trial, Fred Hutch scientists led by Dr. Seth Pollack see signs of immune attack after injections of a bacteria-inspired drug.
– Fred Hutchinson Cancer Research Center
American Association for Cancer Research, April 1-5
Embargo expired on 03-Apr-2017 at 13:00 ET


Ladies, This Is Why Fertility Declines with Age
Age-related female infertility explained by a defect in the choreography of chromosome sharing during cell division in eggs before they are fertilized.
– Universite de Montreal
Current Biology, April 2017.Canadian Institutes of Health Research MOP142334J.-Louis Lévesque Foundation and the Canada Foundation for Innovation FCI32711
Embargo expired on 03-Apr-2017 at 12:00 ET


Typologies: Women Drinkers Are More Diverse Than Men Drinkers
People drink alcohol for a number of reasons. This study focused on understanding why people drink and the consequences of their drinking. First, researchers identified “clusters” of drinkers in New Zealand, based on how much alcohol they drank, ...
– Research Society on Alcoholism
Alcoholism: Clinical and Experimental Research
Embargo expired on 03-Apr-2017 at 17:00 ET


Study Finds More Childhood Cancer Survivors Would Likely Benefit From Genetic Screening
St. Jude Children’s Research Hospital has completed the first whole genome sequencing of cancer survivors and found that 12 percent of childhood cancer survivors carry mutations linked to an increased risk of cancer
– St. Jude Children's Research Hospital
CA195547
Embargo expired on 03-Apr-2017 at 15:00 ET


Higher Anabolic Hormone Levels Predict Lower Risk of Worsening Frailty in Men
A new study suggests that middle-age and elderly men are less likely to develop worsening frailty if they have high levels of certain anabolic hormones, which are muscle- and bone-building hormones. The study results will be presented Sunday at ENDO ...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 10:00 ET


New Simple Tool Can Help Identify People at High Risk for Prediabetes
The time to maximal sugar level during an oral glucose tolerance test is associated with higher risk for prediabetes and could give important information about the ability of the pancreas to secrete insulin, according to research presented at the End...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 11:15 ET


New Natural Estrogen-Progesterone Capsule Reduces Postmenopausal Hot Flashes
A natural, or bioidentical, combined estradiol-progesterone capsule (TX-001HR) significantly decreases the frequency and severity of moderate to severe hot flashes in postmenopausal women, the Replenish study finds. Results of this phase 3, randomize...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 11:15 ET


Low-Calorie Sweeteners Promote Fat Accumulation in Human Fat
Low-calorie, artificial sweeteners appear to play havoc with the body’s metabolism, and large consumption of these sugar substitutes could promote fat accumulation, especially in people who are already obese, preliminary research suggests. The stud...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 11:15 ET


Patients with Higher Thyroid Hormone Levels Lose More Weight After Bariatric Surgery
Patients who have higher levels of the thyroid hormone triiodothyronine (T3) lose more weight after bariatric surgery, new research from Portugal reports. The study results will be presented in a poster Monday, April 3, at ENDO 2017, the annual meeti...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 13:00 ET


Hormones Are Behind Hernias of the Groin in Elderly Men, Study Suggests
Researchers have identified an apparent cause of inguinal hernia, or groin hernia, in older men: altered sex hormone levels that weaken and scar muscle tissue in the lower abdomen. Results of their study using an animal model will be presented Monday...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 10:00 ET


Estetrol (E4) Shows Promise as a Safe, Effective Drug for Use in Advanced Prostate Cancer
The natural fetal estrogen estetrol, also called E4, is being tested as a new drug that may help treat advanced prostate cancer, according to an ongoing industry-sponsored study from the Netherlands. The final results will be presented in a poster on...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 10:00 ET


Program Equips Rural Primary Care Providers to Manage Complex Diabetes
Primary care providers (PCPs) and community health workers in rural areas of New Mexico gained confidence in in their ability to manage patients with complex diabetes by participating in a videoconferencing educational program led by diabetes special...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 11:00 ET


Artificial Pancreas Improves Blood Sugar Control in Young Kids
An artificial pancreas, which delivers insulin in an automated way to individuals with type 1 diabetes, appears to be safe and effective for use in children ages 5 to 8 years, a new study finds. Results will be presented Tuesday at the Endocrine Soci...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 11:00 ET


In the United States Military, White Kids and Officers' Kids More Likely to Use Diabetes Control Technology
Even with equal access to healthcare in the United States military, significant disparities in caring for children with type 1 diabetes still exist, new research reports. The results of the study will be presented Monday, April 3, at ENDO 2017, the a...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 13:00 ET


Diabetes Control Is More Difficult for Night Shift Workers
People with type 2 diabetes have poorer control over their blood glucose levels when they work the night shift compared with those who work in the daytime or are unemployed, a new study finds. The study results, to be presented Monday at the Endocrin...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 13:00 ET


Brain Signals After a Meal Respond to Food Pictures More in Obese Than Lean Kids
Brain signals that should help tell us we are full after eating appear to be dulled in obese children, according to preliminary results of a new study being presented Monday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla....
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 13:00 ET


Magnetic Brain Stimulation Causes Weight Loss by Making Gut Bacteria Healthier
A new study finds that a noninvasive electromagnetic brain stimulation technique helps obese people lose weight, partly by changing the composition of their intestinal bacteria—the so-called gut microbiota. Results of the technique, called deep tra...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 11:00 ET


Traumatic Brain Injuries Leave Women Prone to Mental Health Problems
Traumatic brain injuries affect the body’s stress axis differently in female and male mice, according to research presented at the Endocrine Society’s 99th annual meeting, ENDO 2017, in Orlando, Fla. The results could help explain why women who e...
– Endocrine Society
ENDO 2017, Apr-2017
Embargo expired on 03-Apr-2017 at 13:00 ET


Biomarker Identified for Likely Aggressive, Early Stage Breast Cancer
Whitehead Institute scientists have identified a gene that could help clinicians discern which patients have aggressive forms of early stage breast cancer, which could prevent hundreds of thousands of women from undergoing unnecessary treatment and s...
– Whitehead Institute for Biomedical Research
PNAS, Apr-20171122374
Embargo expired on 03-Apr-2017 at 15:00 ET


Stand Up to Cancer Innovation Grant Funds MD Anderson Microbiome Study
An Innovative Research Grant from Stand Up to Cancer will help a University of Texas MD Anderson Cancer Center physician scientist and her team understand how the bacteria in the digestive tracts of melanoma patients affects their response to a commo...
– University of Texas M. D. Anderson Cancer Center
Embargo expired on 03-Apr-2017 at 12:00 ET


New Tool Uses Behavioral Cues to Assess Pain in ICU Patients Who Can't Communicate
A new Behavior Pain Assessment Tool (BPAT) provides a simple way to evaluate pain in critically ill patients—including those who aren't able to communicate their pain verbally, reports a study in PAIN®, the official publication of the Internationa...
– Wolters Kluwer Health: Lippincott Williams and Wilkins
Pain


Gallbladder Removal Is Common. But Is It Necessary?
Johns Hopkins researchers say that the findings they published in the current edition of The American Journal of Gastroenterology could have important implications for the field of personalized medicine.
– Johns Hopkins Medicine
The American Journal of Gastroenterology


Examination of Diabetes and Cholesterol Drugs in Pancreatic Cancer Mortality Shows Improved Survival with Use of One More Than the Other
Research has shown that by themselves, the diabetes drug metformin and cholesterol-lowering drugs known as statins are associated with reduced cancer mortality, but little is known about the effect on pancreatic cancer mortality when these drugs are ...
– Rutgers Cancer Institute of New Jersey
AACR Annual Meeting 2017


Researchers Document How Melanoma Tumors Form
University of Iowa researchers have documented in continuous, real time how melanoma cells form tumors. The team report the process is similar to that of breast cancer cells and have successfully screened for two antibodies that stopped tumor formati...
– University of Iowa
PLOS One, March 2017


Diagnosis of and Care for Heart Attacks Could Be Advanced by New Study Published in AACC’s Journal of Applied Laboratory Medicine
A study published today in AACC’s Journal of Applied Laboratory Medicine describes the creation of a first-of-its-kind patient sample bank that could improve consistency among blood tests used to diagnose heart attacks and advance care for cardiac ...
– American Association for Clinical Chemistry (AACC)
Journal of Applied Laboratory Medicine, April-2017


Risk of Data Breaches at Hospitals Is Greater at Larger Facilities and Those with Major Teaching Mission
The risk of data breaches at U.S. hospitals is associated with larger facilities and hospitals that have a major teaching mission, according to a study published online today by JAMA Internal Medicine.
– Johns Hopkins University Carey Business School
JAMA Internal Medicine


UNH Research Finds Eroding Trust in Scientists Could Hinder Efforts to Stop Zika
Nearly half of New Hampshire residents surveyed believe scientists adjust their findings to get the answers they want, and these people are significantly less likely to trust the Centers for Disease Control (CDC) as a source of information on the Zi...
– University of New Hampshire


Stress a Common Seizure Trigger in Epilepsy, UC Study Affirms
A recent review article in the European journal Seizure, by researchers at University of Cincinnati Epilepsy Center at the UC Gardner Neuroscience Institute, looks at the stress-seizure relationship and how adopting stress reduction techniques may pr...
– University of Cincinnati (UC) Academic Health Center
Seizure - European Journal of Epilepsy , Volume 44 , 2017


Some Head and Neck Cancer Patients Benefit From Continued Checkpoint Inhibitor Treatment After Tumor Growth
New research suggests that some patients with head and neck cancers can benefit by continuing treatment with an immunotherapy drug after their tumors show signs of enlargement according to investigators at Dana-Farber Cancer Institute and other organ...
– Dana-Farber Cancer Institute
AACR annual meeting


Drug Combination Boost PARP Inhibitor Response in Resistant Ovarian Cancer
New Dana-Farber study shows patients with platinum resistant ovarian cancer who wouldn’t be expected to respond to a PARP inhibitor had partial shrinkage of their tumor with the addition of a kinase inhibitor.
– Dana-Farber Cancer Institute


Drug Combination Shows Benefit in RAS-Driven Cancers
Dana-Farber Cancer Institute scientists report a number of patients in a small study with RAS-driven lung, ovarian, and thyroid cancers got long-term clinical benefit from a combination of two drugs that targeted molecular pathways controlled by the ...
– Dana-Farber Cancer Institute


‘Doctor’ Robot Could Help Solve Sports-Concussion Dilemma in Rural America
From bustling cities to tiny farming communities, the bright lights of the local stadium are common beacons to the Friday night ritual of high school football.
– UT Southwestern Medical Center
Neurology, Mar-2017


Mayo Clinic Monthly News Tips
Mayo Clinic Monthly News Tips March 2017 Headlines
– Mayo Clinic


NCCN Imaging Appropriate Use Criteria Published for 13 Additional Guidelines
NCCN Imaging AUC™ provide a single access point for all oncology imaging recommendations within the NCCN Guidelines®; currently, NCCN Imaging AUC™ are available for 48 NCCN Guidelines.
– National Comprehensive Cancer Network® (NCCN®)


Man Moves Paralyzed Legs Using Device That Stimulates Spinal Cord
Mayo Clinic researchers used electrical stimulation on the spinal cord and intense physical therapy to help a man intentionally move his paralyzed legs, stand and make steplike motions for the first time in three years.
– Mayo Clinic


Excessive Throwing Puts Baseball Players at Risk
When the pros take the field today for Opening Day, many of the sport’s Little League and high school athlete counterparts also will be back in action. With that, however, comes a hazard that doesn’t discriminate by a player’s age or skill leve...
– Michigan Medicine - University of Michigan


First-in-Human Stem Cell Clinical Trial for Spinal Injury Expands
Phase I clinical trial evaluating safety of neural stem cell transplantation being expanded to four more qualifying participants.
– University of California San Diego Health


10 Things You Need to Know After Your Child Is Diagnosed with Autism
In recognition of Autism Awareness Month, Dr. Catherine Lord, director of the Center for Autism and the Developing Brain at NewYork-Presbyterian, Weill Cornell Medicine and Columbia University Medical Center in collaboration with New York Collaborate...
Expert Available
– New York-Presbyterian Hospital


$118.9 Million Health Care Simulation Center to Change Traditional Way Students in the Health Professions Learn
Health care is emerging as one of the largest global virtual and augmented reality markets outside of the video gaming industry. What aviation simulation did for the flight industry, these new technologies will do for health care education in the new...
– University of Nebraska Medical Center (UNMC)


ISPOR Announces 2017 Scientific Achievement and Leadership Awards
The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) announced the recipients of its 2017 Scientific Achievement and Leadership Awards.
– International Society for Pharmacoeconomics and Outcomes Research (ISPOR)
ISPOR Scientific Achievement Awards


Intermountain Healthcare Awarded National 2017 Hearst Health Prize
Hearst Health, a division of Hearst, and the Jefferson College of Population Health of Thomas Jefferson University, have announced that Utah-based Intermountain Healthcare is the winner of the 2017 Hearst Health Prize.
– Intermountain Medical Center


Wolters Kluwer’s Lippincott Solutions Offers New Online Courses Supporting the Joint Commission’s Advanced Certification in Joint Replacement
Wolters Kluwer, a leading global provider of information and point of care solutions for the healthcare industry, today announced the release of eight new online courses designed to help organizations with the requirements of The Joint Commission’s...
– Wolters Kluwer Health: Lippincott Williams and Wilkins


Two Penn Physicians Awarded SU2C Immuno-Oncology Innovative Research Grants
Two doctors in the Perelman School of Medicine at the University of Pennsylvania have been awarded Immuno-Oncology Innovative Research Grants (IRG) by Stand Up to Cancer (SU2C). Michael Farwell, MD, an assistant professor of Radiology, and Gregory L....
– Perelman School of Medicine at the University of Pennsylvania


ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before
The newest release of ACR Appropriateness Criteria® covers 230 topics with more than 1,100 clinical indications.
– American College of Radiology (ACR)


New Book Spotlights Health Disparities for South Asian Americans
Dr. Memoona Hasnain, professor of family medicine at the University of Illinois at Chicago, is the lead editor of a new book about the health of South Asian Americans.
– University of Illinois at Chicago


New Research Project to Improve Oral Health of Arizona’s Preschoolers
A consortium of NAU researchers are looking into Arizona's dental caries epidemic to find answers into the increased rate of tooth decay in the state.
– Northern Arizona University


Keck School of Medicine of USC Names John S. Oghalai, MD, FACS New Chair of USC Tina and Rick Caruso Department of Otolaryngology – Head and Neck Surgery
Keck School of Medicine of the University of Southern California (USC) has named John S. Oghalai, MD, FACS, the new chair of the Tina and Rick Caruso Department of Otolaryngology – Head and Neck Surgery, effective Aug. 1, 2017.
– Keck Medicine of USC


Mount Sinai Researchers Receive Major NIH Award for Autism Genetics Research
$2.5 million grant extends Autism Sequencing Consortium through 2022 to collect genetic data of more than 50,000 individuals
– Mount Sinai Health System


Case Western Reserve Named to New National Colorectal Cancer Dream Team
Case Western Reserve University School of Medicine and the Case Comprehensive Cancer Center have been named to a new colorectal cancer dream team that was announced today at the annual meeting of the American Association for Cancer Research in Washin...
– Case Western Reserve University


‘Innovator’ Award for New Leukemia Immunotherapies
Dr. Marie Bleakley, a pediatric oncology physician-scientist at Fred Hutchinson Cancer Research Center, has received a 2017 Innovative Research Grant in immuno-oncology from Stand Up To Cancer.
– Fred Hutchinson Cancer Research Center
American Association for Cancer Research


Pioneering Investigators in Experimental Heart Stem Cell and Cancer Therapies Recognized
Two prominent Cedars-Sinai investigators — one leading the development of biological treatments for heart disease, the other spearheading the design and analysis of clinical trials for cancer research — were inducted April 3 into the Johns Hopkin...
– Cedars-Sinai


Addressing Urban Health Challenges and Opportunities on a Global Scale
“Urban Health: A Global Challenge" is a free satellite session on April 6, organized by Georgetown University, the International Society for Urban Health, and the New York Academy of Medicine. The session precedes the 2017 Annual CUGH Global Health...
– Georgetown University Medical Center

Science News


Hair Strands Could Reveal Lifestyle Secrets of Criminals (Video)
Hair fiber analysis, a forensic crime tool with a questionable past, could soon have a brighter future thanks to the development of a more refined scientific technique that could reveal much about a person’s lifestyle. Scientists say the new techni...
– American Chemical Society (ACS)
253rd National Meeting & Exposition of the American Chemical Society
Embargo expired on 04-Apr-2017 at 05:00 ET


Bio-Sensing Contact Lens Could Someday Measure Blood Glucose, Other Bodily Functions
Transparent biosensors embedded into contact lenses could soon allow doctors and patients to monitor blood glucose levels and a host of other telltale signs of disease without invasive tests. Scientists say the bio-sensing lenses, based on technology...
– American Chemical Society (ACS)
253rd National Meeting & Exposition of the American Chemical Society
Embargo expired on 04-Apr-2017 at 05:00 ET


Materials May Lead to Self-Healing Smartphones
Taking a cue from the Marvel Universe, researchers report that they have developed a self-healing polymeric material with an eye toward electronics and soft robotics that can repair themselves.
– American Chemical Society (ACS)
253rd National Meeting & Exposition of the American Chemical Society
Embargo expired on 04-Apr-2017 at 05:00 ET


Stopping Zika From Crossing the Placenta
Although the World Health Organization ended its global health emergency on Zika last November, the virus could still make a comeback as temperatures get warmer and mosquito season ramps up.
– American Chemical Society (ACS)
253rd National Meeting & Exposition of the American Chemical Society
Embargo expired on 04-Apr-2017 at 05:00 ET


Photonic Crystal and Nanowire Combo Advances 'Photonic Integration'
While bigger nanowires can improve light confinement and performance, it increases both energy consumption and device footprint -- both of which are considered “fatal” when it comes to integration. Addressing this problem, researchers came up wit...
– American Institute of Physics (AIP)
Embargo expired on 03-Apr-2017 at 11:00 ET


Domesticated Rice Goes Rogue
We tend to assume that domestication is a one-way street and that, once domesticated, crop plants stay domesticated. A new study of rice shows, however, that different methods of farming change the evolutionary pressures on crop plants, and the plant...
– Washington University in St. Louis
Nature Genetics, April 3, 2017
Embargo expired on 03-Apr-2017 at 11:00 ET


Speciation Driven by Alleles Adapted to Local Conditions
Using the flowering mustard plant Boechera stricta, a team including researchers at the DOE Joint Genome Institute and Duke University offers the first direct evidence showing that QTLs, genome regions on chromosomes to which genetic traits can be ma...
– Lawrence Berkeley National Laboratory
Embargo expired on 03-Apr-2017 at 11:00 ET


New Study Finds Political Echo Chambers in Consumption of Science
Reader preferences for liberal or conservative political books also attract them to different types of science books, according to a new study. The result supports observations that the divisiveness of politics in the United States has spread to scie...
– Computation Institute
Nature Human Behaviour
Embargo expired on 03-Apr-2017 at 11:00 ET


Soil in HD, New Fossil Finds, Toxic Fishing, Reducing Waste, and More in the Environmental Science News Source
The latest research on the environment in the Environmental Science News Source
– Newswise



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